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Medications used in the management of pulmonary arterial hypertension ( B01, C02 ).The major product of metabolisation by these enzymes is N-desmethylated sildenafil, which is metabolised further.What links here Related changes Upload file Special pages Permanent link Page information Wikidata item Cite this page.Viagra Fast Tabs Soft India Mexico Avaiable Shipping Generic Sildenafil With. Generic Viagra Soft Tabs India.Instead Sylvester McCoy was 4 Acetoxy MIPT 5 blond wig with his the only Buy generic Viagra online pharmacy school.Sildenafil should not be used if sexual activity is inadvisable due to underlying cardiovascular risk factors (such as recent heart surgery, stroke or heart attack, etc.).

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Psychostimulants (e.g., amphetamines, cocaine, methylphenidate ).Nitric oxide (NO) in the corpus cavernosum of the penis binds to guanylate cyclase receptors, which results in increased levels of cGMP, leading to smooth muscle relaxation ( vasodilation ) of the intimal cushions of the helicine arteries.It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease ).

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Common side effects include headaches and heartburn, as well as flushed skin.Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects.Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection.

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Rare but serious side effects include prolonged erections, which can lead to damage to the penis, and sudden-onset hearing loss.