A sudden drop in blood pressure can cause you to feel dizzy, faint, or have a heart attack or stroke.Some people may also have ringing in their ears (tinnitus) or dizziness.Results with all doses have been pooled, but scores showed greater improvement at the 50 and 100 mg doses than at 25 mg.Side effects are no longer in using Viagra so you can use it without any trouble.Others were reported to have occurred hours to days after the use of Viagra and sexual activity.

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Co-administration of ritonavir, a strong CYP3A4 inhibitor, greatly increased the systemic exposure of sildenafil (11-fold increase in AUC).

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet.Metabolic and Nutritional: thirst, edema, gout, unstable diabetes, hyperglycemia, peripheral edema, hyperuricemia, hypoglycemic reaction, hypernatremia.One patient discontinued the study prematurely due to an adverse event of hypotension following dosing with Viagra 50 mg.

Administration of Viagra with nitric oxide donors such as organic nitrates or organic nitrites in any form is contraindicated.The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range.

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Sixty-three percent, 74%, and 82% of the patients on 25 mg, 50 mg and 100 mg of Viagra, respectively, reported an improvement in their erections, compared to 24% on placebo.

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A total dose of 40 mg sildenafil was administered by four intravenous infusions.Cardiovascular: angina pectoris, AV block, migraine, syncope, tachycardia, palpitation, hypotension, postural hypotension, myocardial ischemia, cerebral thrombosis, cardiac arrest, heart failure, abnormal electrocardiogram, cardiomyopathy.In the first study, a single oral dose of Viagra 100 mg or matching placebo was administered in a 2-period crossover design to 4 generally healthy males with benign prostatic hyperplasia (BPH).The following are discussed in more detail in other sections of the labeling.

In many of the studies, of both fixed dose and titration designs, daily diaries were kept by patients.The following adverse reactions have been identified during post approval use of Viagra.Many of these events were reported to occur during or shortly after sexual activity, and a few were reported to occur shortly after the use of Viagra without sexual activity.

Figure 1: Mean Change from Baseline in Sitting Systolic Blood Pressure, Healthy Volunteers.If Viagra is prescribed to patients taking ritonavir, caution should be used.Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance.

Stepwise increase in alpha-blocker dose may be associated with further lowering of blood pressure when taking a PDE5 inhibitor.The use of Viagra offers no protection against sexually transmitted diseases.Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg.A drug intended for men, the impact of Viagra on women and female.In placebo-controlled clinical studies, the discontinuation rate due to adverse reactions for Viagra (2.5%) was not significantly different from placebo (2.3%).In studies with healthy volunteers of single doses up to 800 mg, adverse reactions were similar to those seen at lower doses but incidence rates and severities were increased.This eMedTV segment describes how Viagra works to treat ED, and also covers off-label.Viagra is used primarily to treat erectile dysfunction (ED), or impotence.These effects on the metabolite are not expected to be of clinical consequence.

If you have these symptoms, stop taking Viagra and contact a doctor right away.

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The concomitant administration of the protease inhibitor ritonavir substantially increases serum concentrations of sildenafil (11-fold increase in AUC).In fixed-dose studies, the incidence of some adverse reactions increased with dose.Viagra is a prescription medicine used to treat erectile dysfunction (ED).There have been postmarketing reports of bleeding events in patients who have taken Viagra.This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% of the parent drug.No severe adverse events potentially related to blood pressure effects were reported in this group.Effects of Viagra on Vision: At single oral doses of 100 mg and 200 mg, transient dose-related impairment of color discrimination was detected using the Farnsworth-Munsell 100-hue test, with peak effects near the time of peak plasma levels.

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There were no reports of postural dizziness or orthostatic hypotension.Hemic and Lymphatic: vaso-occlusive crisis: In a small, prematurely terminated study of REVATIO (sildenafil) in patients with pulmonary arterial hypertension (PAH) secondary to sickle cell disease, vaso-occlusive crises requiring hospitalization were more commonly reported in patients who received sildenafil than in those randomized to placebo.The primary measure in the principal studies was a sexual function questionnaire (the International Index of Erectile Function - IIEF) administered during a 4-week treatment-free run-in period, at baseline, at follow-up visits, and at the end of double-blind, placebo-controlled, at-home treatment.Cimetidine (800 mg), a nonspecific CYP inhibitor, caused a 56% increase in plasma sildenafil concentrations when co-administered with Viagra (50 mg) to healthy volunteers.

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The mean profiles of the change from baseline in standing systolic blood pressure in subjects treated with doxazosin in combination with 50 mg Viagra or matching placebo are shown in Figure 3.FDA: Cutting-Edge Technology Sheds Light on Antibiotic Resistance.Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state.Ask your doctor if your heart is healthy enough to handle the extra strain of having sex.